RNA Details
Disease Name
heart failure
Tissue
heart
RNA Symbol
BMP7
RNA ID
RNA Type
mRNA
Alteration Pattern
hyper methylation
Species
homo sapiens
Detection Methods
PCR; dual-luciferase reporter assay etc.
Target
NA
Pathway
NOTCH SIGNALING PATHWAY
PubMed ID
Title
Endocardial fibroelastosis is caused by aberrant endothelial to mesenchymal transition
Year
2015
Function
Highly methylated bmp-7 can block the end epithelial-mesenchymal transition (EMT) induced by TGF-beta and reduce fibrosis by regulating the activity of ve cadherin promoter.